Palmitoyl tripeptide 5 hauv kev tu tawv nqaij(CAS: 623172-56-5), raws li qhov ntxov tshaj plaws thiab feem ntau siv teeb liab raws li kev zoo nkauj peptide, ua kom muaj kev loj hlob ntawm kev hloov pauv - (TGF - ) txoj hauv kev los ntawm kev ua raws li cov platelet reactive protein-1 (TSP-1), + ua kom muaj kev sib txuas ntawm cov kab sib txuas ntawm dual kev degradation". Nws yog ib qho tseem ceeb ntawm daim tawv nqaij rejuvenation nrog TGF - txoj hauv kev raws li nws cov tub ntxhais, collagen synthesis raws li nws lub ntsiab tseem ceeb, MMP inhibition raws li nws cov kab kev tiv thaiv, antioxidant thiab whitening raws li nws tis, thiab anti-inflammatory thiab kho raws li nws qhov tob. Los ntawm hom I, III, IV collagen rau elastin, hyaluronic acid, glycosaminoglycans, fibronectin, los ntawm tyrosinase inhibition mus rau dawb radical scavenging, los ntawm lub ntsej muag wrinkle kuj mus intimate zawm.
Palmitoyl Tripeptide-5 COA
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| Certificate of Analysis | ||
| Compound npe | Palmitoyl Tripeptide-5 | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 623172-56-5 | |
| Ntau | 80g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202601090067 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2029 | |
| qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.58% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.49% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.98% |
| Ib qho impurity | <0.8% | 0.68% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 140 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 400ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab 2-8 degree | |
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| Chemical Formula: | C35H66F3N5O7 |
| Exact Mass: | 725 |
| Molecular Luj: | 726 |
| m/z: | 725 (100.0%), 726 (37.9%), 727 (4.3%), 727 (2.7%), 726 (1.8%), 727 (1.4%) |
| Elemental Analysis: | C, 57.91; H, 9.16; F, 7.85; N, 9.65; O, 15.43 |
Palmitoyl Tripeptide 5 siv
Lub essence ntawm daim tawv nqaij laus yog qhov tsis txaus ntawm extracellular matrix (ECM) - txo collagen synthesis thiab ceev degradation.Palmitoyl tripeptide 5 hauv kev tu tawv nqaij, tseem hu ua SYN ®- COLL, Pal-KVK, Tsim los ntawm lysine valine lysine tripeptide ua ke nrog palmitic acid, nrog rau qhov hnyav molecular ntawm 611.92 thiab molecular mis ntawm C33H65N5O5. Nws pab pawg palmitoyl endows zoo heev transdermal muaj peev xwm, thaum lub sij hawm tripeptide ua kom raug simulates TSP -1 muaj nuj nqi, tso active TGF - thiab pib lub collagen synthesis program ntawm fibroblasts.
Ua kom collagen synthesis - thawj lub cav rau kev tiv thaiv wrinkle thiab firming
Qhov no yog qhov tseem ceeb tshaj plaws thiab siv tau yooj yim.
Txhawb kev sib txuas ntawm hom I, III, thiab IV collagen: Palmitoyl tripeptide-5 simulates qhov khi ntawm TSP-1 mus rau qhov tsis muaj zog ua ntej ntawm TGF - , tso tawm TGF nquag - thiab ncaj qha upregulating cov noob qhia ntawm hom I, III, thiab IV collagen hauv fibroblast . Kev ntsuam xyuas ntawm daim tawv nqaij hauv vitro pom tau tias ntau dua lossis sib npaug ntawm 2.5ppm tuaj yeem txhawb hom I collagen synthesis, thiab 5ppm muaj cov nyhuv tib yam li TGF - 1; Ntau dua los yog sib npaug rau 0.63ppm tuaj yeem txhawb kev sib txuas ntawm hom IV collagen thiab ntxiv dag zog rau cov txheej txheem epidermal hlws ris. Raws li kev sim thib peb tib neeg, kev siv tsis tu ncua rau 28 hnub ua rau 19.6% nce hauv collagen ntom hauv cov dermis ntawm cov ntsiab lus thiab 22.3% txo qis hauv qhov tob tob tob.
QPCR tshawb pom tau lees paub tias nws tuaj yeem txhim kho qhov kev qhia ntawm qhov tseem ceeb hauv TGF - txoj hauv kev, txhawb kev ua haujlwm fibroblast, thiab nce collagen synthesis muaj peev xwm los ntawm 119% piv rau qhov zoo tswj TGF - .
Cov ntaub ntawv kho mob sib piv: Hauv kev sim tswj ntawm 60 tus neeg ua haujlwm noj qab haus huv, 2.5%palmitoyl tripeptide 5 hauv kev tu tawv nqaijcream pab pawg tau siv ob zaug ib hnub rau 84 hnub. Qhov nruab nrab roughness (Ra) thiab qhov siab tshaj plaws roughness (Rz, Rt) tsis zoo ntawm daim tawv nqaij saum npoo tau zoo dua, thiab cov nyhuv zoo dua li cov concentration ntau dua palmitoyl tripeptide-3 pawg. Wrinkle ntsig txog qhov ntsuas tau txo qis los ntawm 12%.
Nws txoj kev ua tau zoo yog zoo ib yam li vitamin A acid, tab sis tsis muaj cov kev mob tshwm sim ntawm vitamin A acid xws li tev, liab, thiab photosensitivity, nws yog ib qho zoo tagnrho rau kev tiv thaiv - laus rhiab cov leeg.
Inhibition ntawm matrix metalloproteinases - "gatekeeper" uas thaiv collagen degradation
Inhibition ntawm MMP-1 thiab MMP-3: Cov kev tshawb fawb hauv vitro tau pom tias palmitoyl tripeptide-5 tuaj yeem cuam tshuam nrog collagen degradation mediated los ntawm MMP-1 thiab MMP-3, nrog tus nqi inhibition ntawm 82%, tiv thaiv collagen uas twb muaj lawm los ntawm kev degraded ntawm qhov chaw.
Inhibition ntawm MMP-2 thiab MMP-9: Hauv kev sim enzymatic, qhov ua tau zoo inhibitory concentration (IC50) ntawm MMP-2/9 yog nyob rau theem nanomolar (nM), qhia txog nws cov kev ua haujlwm siab. Ceev txo kev puas tsuaj rau hom I thiab IV collagen uas twb muaj lawm, muab kev txhim kho tam sim hauv cov kab zoo.
Downregulation ntawm inflammatory yam: ib txhij inhibiting zus tau tej cov interleukin -8 (IL-8) thiab qog necrosis factor - (TNF -), tiv thaiv collagen los ntawm degradation ntawm lub inflammatory theem.
Lub dual channel mechanism ntawm "txhim kho synthesis + inhibiting degradation" ua rau nws cov nyhuv antiwrinkle nyob deb superior rau ntawm ib qho ntxiv cov khoom xyaw.
Txhawb nqa elastin synthesis - tsim cov tawv nqaij elastic network
Collagen muab cov tawv nqaij toughness, thaum elastin muab cov tawv nqaij resilience. Thaum txhawb collagen synthesis, nws ho nce zus tau tej cov elastin. Ob leeg ua haujlwm ua ke los tsim kom muaj kev sib koom ua tiav ntawm daim tawv nqaij, ua rau cov tawv nqaij tsis yog "plum" tab sis kuj "elastic". Kev tshawb fawb tau pom tias nws tuaj yeem cuam tshuam nrog cov txheej txheem tsim khoom elastin, ua rau muaj kev cuam tshuam tag nrho ntawm cov tawv nqaij noo noo, txhim kho cov kab zoo, thiab ua kom tawv nqaij.
Txhawb nqa cov synthesis ntawm hyaluronic acid - lub cav tsis pom kev rau kev sib sib zog nqus dej
Yuav ua kom cov synthesis ntawm hyaluronic acid (HA) nyob rau hauv lub intercellular matrix. Hyaluronic acid yog lub hauv paus moisturizing molecule nyob rau hauv lub intercellular matrix, thiab nws cov ntsiab lus ncaj qha txiav txim siab℃ntawm daim tawv nqaij hydration. Qhov no txhais tau hais tias palmitoyl tripeptide-5 tsis tsuas yog tiv thaiv wrinkles, tab sis kuj "kho dej" sab hauv, ua kom cov tawv nqaij noo noo, rov qab smoothness thiab firmness, txhim kho cov tawv nqaij, thiab txhim kho radiance thiab pob tshab.
Hauv daim ntawv thov, nws raug pom zoo kom sib xyaw nrog hyaluronic acid: 2-10ppm palmitoyl tripeptide-5+hyaluronic acid, uas tuaj yeem ua tiav cov txiaj ntsig zoo ntawm "collagen regeneration + instant filling".
Txhawb nqa cov synthesis ntawm glycosaminoglycans thiab fibronectin - txhim kho lub extracellular matrix
Nws kuj tseem tuaj yeem ua rau muaj kev tsim cov glycosaminoglycans (GAGs) thiab fibronectin. Ob hom tshuaj no yog cov khoom tseem ceeb ntawm cov kab mob extracellular matrix, koom nrog hauv cell signaling thiab kho cov ntaub so ntswg. Tej zaum yuav ua rau kom cov tiam ntawm ob qho tib si, ntxiv txhim kho cov txheej txheem kev ncaj ncees ntawm daim tawv nqaij thiab ua tiav kev rov zoo ntawm daim tawv nqaij ntawm qib microscopic.
Antioxidant - ib qho tseem ceeb quab yuam kom tshem tawm cov dawb radicals
Ob lub ntsiab culprits ntawm daim tawv nqaij laus yog collagen poob thiab oxidative puas. Muaj pov thawj txaus rau yav dhau los, thiab nws kuj ua tau zoo heev nyob rau tom kawg.
Clearing oxygen thiab hydroxyl radicals:Palmitoyl tripeptide 5 hauv kev tu tawv nqaijtuaj yeem txhawb kev loj hlob ntawm daim tawv nqaij thiab inhibit kev puas tsuaj ntawm matrix proteins los ntawm oxygen thiab hydroxyl radicals. Cov kev tshawb fawb soj ntsuam tau pom tias nws lub peev xwm antioxidant yog 4 npaug ntawm cov vitamin C thiab 2 npaug ntawm cov vitamin E.
Los tiv thaiv UVB lub teeb puas: Master's thesis tshawb fawb qhia tau hais tias collagen peptides tuaj yeem txhim kho lub cev tiv thaiv kab mob hauv UVB kev puas tsuaj qauv, thiab tus po thiab thymus indices nce ntxiv, qhia tias lawv tuaj yeem tsis tsuas "kho" lub teeb puas, tab sis kuj "tiv thaiv" lub teeb puas los ntawm kev tiv thaiv kab mob.
Cov ntaub ntawv
Cov ntaub ntawv
[1] Sohu lub vev xaib Palmitoyl tripeptide-5 yog qhov tseem ceeb rau kev tiv thaiv kev laus [EB/OL]. 2022-09-16
[2] Gao Yaqian, Tang Jian, Wang Zhiyong, thiab lwm yam Kev tshawb fawb ntawm daim tawv nqaij Whitening Efficacy thiab Mechanism ntawm Palmitoyl Tripeptide-5 [J]. Kev Lag Luam Tshuaj Txhua Hnub, 2018, 48 (3): 166-171
[3] Peptide Biology [Targeted Anti Wrinkle Black Technology] Palmitoyl Tripeptide-5: Collagen Activating Device Penetrating the Keratinum Layer [EB/OL]. Lub Plaub Hlis 25, 2025
[4] Phau 118. Kev tshawb fawb ntawm daim tawv nqaij Whitening Efficacy thiab Mechanism ntawm Palmitoyl Tripeptide-5 [EB/OL]. Lub Ob Hlis 2, 2025
[5] Peptide Biology Palmitoyl Tripeptide-5: Kev Ntsuam Xyuas Cov Khoom Siv Tshuaj Txhuam Hniav thiab Daim Ntawv Thov Kev Pom Zoo [EB/OL]. Cuaj hlis 10, 2025
Cov lus nug nquag
palmitoyl tripeptide-5 siv rau dab tsi?
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Palmitoyl tripeptide-5 kuj tseem siv rau hauv cov khoom siv tshuaj pleev ib ce los tiv thaiv kev laus, vim nws lub peev xwm los txo MMP'S thiab txhawb kev sib txuas ntawm hom I thiab hom II collagen los ntawm extracellular matrix, nrog rau inhibiting melanin ntau lawm los ntawm kev txo cov kev ua ntawm tyrosinase.
Puas yog palmitoyl tripeptide yog retinol?
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Palmitoyl Tripeptide-1 piav qhia
Nws yog categorize raws li ib tug "neeg xa xov liaison peptide" vim hais tias ntawm nws muaj peev xwm "qhia" daim tawv nqaij yuav ua li cas kom zoo, tshwj xeeb tshaj yog hais txog kev txo cov cim ntawm lub hnub puas xws li wrinkles thiab ntxhib ntxhib ntxhib los mos. Qee qhov kev tshawb fawb tau pom tias cov peptide no muaj qhov zoo sib xws los tiv thaiv - cov txiaj ntsig kev laus rau retinol.
Puas yog palmitoyl tripeptide-5 ntuj?
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Palmitoyl Tripeptide-5 yog hluavtaws, patented teeb liab peptide ua los ntawm cov amino acids lysine thiab valine ua ke nrog fatty acid palmitic acid, uas pab nkag mus.
palmitoyl tripeptide-5 ua li cas rau daim tawv nqaij?
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Palmitoyl tripeptide-5 yog ib qho muaj zog hluavtaws los tiv thaiv kev laus peptide uas tob tob rau ntawm daim tawv nqaij los txhawb cov collagen ntau lawm, txhim kho elasticity, thiab cov kab zoo. Los ntawm kev ua raws li lub cev lub cev lub cev, nws pab ua kom tawv nqaij tawv, txo qis wrinkles, thiab tiv thaiv collagen uas twb muaj lawm los ntawm ib puag ncig degradation.
Cov txiaj ntsig ntawm daim tawv nqaij tseem ceeb
Boosts Collagen Synthesis: Nws nquag txhawb koj cov tawv nqaij hlwb (fibroblasts) los tsim collagen ntau dua, muab cov tawv nqaij puv, ua rau cov hluas dua.
Kev ruaj ntseg thiab nqa: Los ntawm kev txhawb nqa ob qho tib si collagen thiab elastin, nws nruj nreem sagging tawv nqaij thiab restores tag nrho elasticity.
Txo Wrinkles: Nws nquag smooths ob txoj kab zoo thiab sib sib zog nqus wrinkles. Cov kev tshawb fawb soj ntsuam pom pom kev txhim kho hauv qhov tob tob thiab kev ntxhib los mos tom qab tsuas yog 4 mus rau 12 lub lis piam ntawm kev siv txhua hnub.
Minimizes Pores: Nws pab ua kom cov tawv nqaij zoo nkauj, uas tuaj yeem pom qhov pom ntawm qhov loj ntawm pores.
Tiv thaiv daim tawv nqaij: Nws inhibits matrix metalloproteinases (MMPs) -enzymes uas paub tias ua kom puas thiab degrade collagen.
Txhim kho dej: Nws pab txhawb cov tawv nqaij extracellular matrix, txhawb kom zoo dua noo noo khaws cia.
Cim npe nrov: palmitoyl tripeptide-5 hauv kev tu tawv nqaij, Tuam Tshoj palmitoyl tripeptide-5 hauv kev tu tawv nqaij manufacturers, lwm tus neeg
