Palmitoyl tripeptide-1 hauv kev tu tawv nqaij(CAS: 147732-56-7, INCI lub npe: Pal GHK), raws li classic matrikine signaling peptide, tau ntev tau muaj koob npe nrov rau nws cov teebmeem tiv thaiv wrinkle thiab firming. Txawm li cas los xij, tsis ntev los no cov kev tshawb fawb thiab kev soj ntsuam soj ntsuam tau pom tias peptide no kuj nthuav tawm ntau qhov sib txawv thiab ntau lub hom phiaj ntawm daim ntawv thov tus nqi hauv thaj tsam ntawm kev ntxuav hniav dawb. Nws yog txoj hauv kev tshawb fawb kom ua tiav cov txiaj ntsig whitening los ntawm tsib lub tswv yim tseem ceeb: txhawb cov cell metabolism rov ua dua tshiab, antioxidant thiab dawb radical scavenging, txhim kho collagen synthesis los txhim kho cov pob tshab pob tshab, kho cov teeb meem los txhim kho cov suab nrov zoo ib yam, thiab dej tob tob thiab ci ntsa iab.
Palmitoyl Tripeptide-1 COA
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| Certificate of Analysis | ||
| Compound npe | Palmitoyl Tripeptide-1 | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 623172-56-5 | |
| Ntau | 80g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202601090067 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2029 | |
| qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.58% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.49% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.98% |
| Ib leeg impurity | <0.8% | 0.68% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 140 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 400ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab 2-8 degree | |
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| Chemical Formula: | C30H54N6O5 |
| Exact Mass: | 578 |
| Molecular Luj: | 579 |
| m/z: | 578 (100.0%), 579 (32.4%), 580 (5.1%), 579 (2.2%), 580 (1.0%) |
| Elemental Analysis: | C, 62.25; H, 9.40; N, 14.52; O, 13.82 |
Palmitoyl Tripeptide 1 siv
Cov pigmentation thiab dullness yog ob qhov tseem ceeb ntawm kev ua kom dawb huv uas ua rau cov neeg Esxias mob plague. Cov khoom xyaw tshuaj pleev ib ce xws li arbutin, vitamin C, niacinamide, thiab lwm yam muaj lawv tus kheej ua tau zoo, tab sis feem ntau muaj kev txwv xws li khaus khaus, tsis muaj zog, thiab kev ua tau zoo ib yam. Nyob rau hauv cov ntsiab lus no, teeb liab raws li kev zoo nkauj peptides, nrog rau lawv "kev tswj hwm" whitening mechanism - tsis ncaj qha tua melanocytes, tab sis pib los ntawm kev sib txuas xws li cell metabolism, oxidative kev nyuaj siab, thiab matrix remodeling - tau qhib ib tug softer thiab ntau check whitening txoj kev tshiab.
Palmitoyl tripeptide-1 hauv kev tu tawv nqaij, tseem hu ua Pal -AHK los yog Matrixyl muaj feem xyuam nrog, yog tsim los ntawm glycine histidine lysine (GHK) tripeptide ua ke nrog palmitic acid, nrog rau qhov hnyav ntawm 578.80 g / mol thiab molecular mis ntawm C ∝₀ H ₅₅ N. Nws Pal-AHK pab pawg muaj peev xwm ua tau zoo tshaj plaws, thaum GHK cov kab ke ua kom raug simulates lub teeb liab peptides hauv tib neeg lub cev, ua rau nws cuam tshuam tob rau hauv cov txheej txheem dermis. Kev tshawb fawb tau pom tias 5ppm concentration ntawm Pal-AHK yog sib npaug li 0.05% vitamin A hauv kev txhawb nqa collagn thiab glycosaminoglycan synthesis, tab sis tag nrho zam qhov stimulation thiab cov kev mob tshwm sim ntawm vitamin A. Cov nyhuv wrinkle tshem tawm thiab kev ua si yog deb tshaj li cov pa vitamin A yam tsis muaj kev phiv. Nws yog qhov tseeb qhov kev ua haujlwm lom neeg zoo heev uas tau maj mam coj mus rau qhov kev tshawb pom thiab kev txhawb nqa dav dav ntawm nws daim ntawv thov whitening.
1. Accelerating cellular metabolic renewal - "superficial rejuvenation" los ntawm qhov chaw
Ib qho ntawm cov laj thawj tseem ceeb rau kev npub sab saum toj yog qhov qeeb ntawm cov metabolism hauv stratum corneum - nkig ntawm cov qub keratin ua rau muaj teeb meem tawg, ua rau dull thiab lifeless superficial. Raws li lub teeb liab peptide, nws tuaj yeem khi rau cov receptors tshwj xeeb ntawm lub ntsej muag ntawm cov hlwb sab nraud, qhib cov kev taw qhia sab hauv, txhawb cov metabolism hauv superficial, thiab txhawb kev loj hlob ntawm tes.
Nws txoj kev ua yog: Pal-AHK → khi rau ntawm tes receptors → ua kom TGF -
txoj hauv kev → txhim kho fibroblast kev ua ub no → accelerating epidermal cell renewal → accelerating shedding of old keratin → sai replenishment of new cells. Qhov "kev hloov pauv nrawm nrawm" no tso cai rau cov laus keratin uas muaj melanin hloov sai dua, yog li ua tiav qhov ci ci ntawm lub suab nrov.
Kev tshawb fawb tau lees paub tias cov kev cai tawm tswv yim tuaj yeem siv rau cov txheej txheem ntawm kev sib txuas cov ntaub so ntswg rov tsim kho thiab kev loj hlob ntawm tes, uas tuaj yeem txhawb kev tsim cov protein ntau ntawm cov khoom siv kho qhov muag thaum lub sij hawm kho superficial piv rau lub cev physiological.
Qhov no txhais tau hais tias nws tsis tsuas yog "hloov lub superficial", tab sis kuj "nourishes lub superficial" thaum hloov lub superficial, ua rau lub tshiab tsim superficial noj qab haus huv thiab pob tshab.
2. Antioxidant thiab dawb radical scavenging - thaiv oxidative discoloration
Lwm qhov ua txhaum rau dull superficial yog oxidative kev nyuaj siab. Cov dawb radicals tsim los ntawm yam xws li hluav taws xob ultraviolet, muaj kuab paug, thiab nyob lig tuaj yeem tua cov cell membranes thiab DNA, txhawb kev ua haujlwm txawv txav ntawm melanocytes, thiab ua kom oxidation ntawm melanin uas twb muaj lawm, tsim "oxidative pigmentation".
Nws muaj cov khoom tseem ceeb antioxidant. GHK ib ntus hauv nws cov molecule nws tus kheej yog ib qho tshwm sim antioxidant tripeptide hauv tib neeg lub cev, uas tuaj yeem tshem tawm cov pa dawb radicals thiab hydroxyl dawb radicals. Kev sim tau pom tias muaj kev pheej hmoo ntawm kev mob siab.
Qhov tseem ceeb tshaj, nws cov khoom antioxidant tsis yog "passive tiv thaiv", tab sis "kev tswj hwm kev ua haujlwm" - nws txhim kho lub ntsej muag ntawm tus kheej cov tshuaj tiv thaiv kab mob antioxidant, txhim kho tag nrho kev ua siab ntev ntawm cov tawv nqaij dawb rau cov dawb radicals, thiab txo qis qhov tshwm sim ntawm oxidative pigmentation. Cov txheej txheem no ua kom ntseeg tau tias nws cov nyhuv whitening tsis vam khom mus tas li
supplementation ntawm sab nraud antioxidants, tab sis theej nkoos lub superficial tus kheej "anti blackening" muaj peev xwm.
3. Txhawb collagen synthesis - txhim khu cov pob tshab thiab radiance
Cov khoom xyaw tshuaj pleev ib ce feem ntau tsom rau "txo melanin", thaum lawv siv txoj hauv kev sib txawv los ntawm kev ua kom cov collagn ua rau lub ntsej muag ntau pob tshab thiab txawm.
Cov txheej txheem yog: txhawb cov synthesis ntawm hom I thiab III collagn, elastin, thiab glycosaminoglycan nyob rau hauv lub dermis → thickening thiab tighter qauv ntawm lub dermis → ntau uniform lub teeb nkag mus → natural "pob tshab" ntawm lub ntsej muag → brighter thiab huv si superficial tone.
Cov ntaub ntawv tshawb fawb qhia tias 5mg / kgpalmitoyl tripeptide-1 hauv kev tu tawv nqaijthiab 500mg / kg retinoic acid muaj cov teebmeem zoo tib yam hauv kev ua kom muaj fiber ntau ntxiv thiab kev qhia siab ntawm collagn hauv cov dermis. Thaum lub collagn matrix ntawm lub ntsej muag yog txaus, tsis tsuas yog ua rau wrinkles txo, tab sis lub suab ntawm lub ntsej muag kuj ib txwm brightens vim kev txhim kho ntawm matrix translucency. Qhov no piav qhia tias yog vim li cas cov neeg siv khoom uas muaj cov tshuaj no feem ntau muab cov lus tawm tswv yim tias lawv cov tawv nqaij tau ci dua - tsis yog tshuaj dawb, tab sis pob tshab los ntawm sab hauv.
Tsis tas li ntawd, nws tuaj yeem txhawb kev sib txuas ntawm laminin thiab fibronectin, uas yog cov khoom tseem ceeb ntawm cov txheej txheem epidermal junction. Lawv txoj kev nplua nuj tuaj yeem ua rau cov epidermis thiab dermis ua kom nruj dua, ntxiv kom txo tau lub teeb tawg thiab txhim kho qhov ci ntsa iab.
4. Kho qhov cuam tshuam sab nrauv - txhim kho cov suab nrov zoo ib yam
Kev puas tsuaj superficial barrier yog tus tua neeg zais uas ua rau cov xim tsis sib xws. Thaum qhov kev ua haujlwm tsis zoo txo qis, qhov poob ntawm cov dej noo nyob sab nraud nrawm dua thiab cov stimuli sab nraud tuaj yeem nkag mus, ua rau mob qis - qib o, uas ua rau muaj qhov txawv txav ntawm melanocytes, tsim cov xim tsis sib xws xws li pigmentation, dullness, thiab ntshav liab streaks.
Lub luag haujlwm ntawm kev kho cov teeb meem tau lees paub dav dav:
Ua kom muaj zog ntawm tes: txhawb nqa fibroblasts los tsim cov collagn thiab mucopolysaccharides, kho qhov muag tob tob, thiab ua kom lub ntsej muag ruaj khov;
Kho tej yam ntuj tso barrier muaj nuj nqi: txhim khu lub superficial lub peev xwm los tiv thaiv sab nraud txawv teb chaws lub cev ntxeem tau thiab tswj cov dej noo;
Anti inflammatory thiab Soothing: Txo cov pigmentation inflammatory los ntawm kev puas tsuaj los ntawm kev tiv thaiv antioxidant thiab tiv thaiv - cov khoom inflammatory.
Tom qab kev kho qhov teeb meem, lub ntsej muag lub peev xwm khaws dej tau zoo dua qub, cov dej noo ntawm cov stratum corneum tau nce, qhov kev xav ntawm lub teeb ntawm lub ntsej muag sab nraud yog qhov sib xws, thiab cov suab nrov ntawm lub ntsej muag zoo ib yam. Kev soj ntsuam soj ntsuam tau pom tias tsis tu ncua ntawm cov khoom siv uas muaj cov tshuaj no txhim kho qhov sib xws ntawm cov neeg siv lub suab nrov thiab txo qhov chaw tsaus.
5. Cov Dej Txhaum Dej Txias Moisturizing - Moisturizing thiab pob tshab
Lub hauv paus kev pom zoo hauv dermatology yog tias 'lub cev qhuav dej ua rau dullness'. Thaum cov dej noo ntawm cov stratum corneum qis dua 10%, qhov saum npoo ntawm lub ntsej muag dhau los ua ntxhib, lub teeb tawg hnyav zuj zus, thiab lub suab nrov nrov tam sim ntawd zoo li npub thiab tsis muaj sia.
Los ntawm kev txhawb cov synthesis ntawm collagn thiab glycosaminoglycans, dej yog khaws cia nyob rau hauv lub dermis txheej: collagn yog ib tug natural moisturizing yam, thaum glycosaminoglycans (xws li hyaluronic acid precursors) yuav khi ib tug loj npaum li cas ntawm cov dej.
Thaum muaj dej txaus nyob rau hauv lub dermis, cov dej yuav kis mus rau lub epidermis, ua kom lub stratum corneum nyob rau hauv tag nrho lub xeev.
Cov kev sim tau pom tias xim av tuaj yeem ua rau cov dej noo ntau ntxiv thiab kaw hauv cov dej noo, ua rau lub ntsej muag zoo li mos thiab du, thiab ua kom lub ntsej muag ci ntsa iab ntawm sab hauv tawm yam tsis muaj dullness. Qhov no "los ntawm sab hauv tawm" txoj kev ci ntsa iab yog txawv kiag li los ntawm cov txheej txheem bleaching ntawm cov khoom xyaw whitening "los ntawm sab nraud hauv" - nws tsis npog dullness, tab sis tshem tawm lub hauv paus ua rau dullness.
6. Kev txhawb nqa cov ntaub ntawv kho mob thiab kev sim
Kev sim 1: Kev txhawb nqa Cell Metabolism
Cov kev sim hauv vitro tau lees paub tias nws tuaj yeem txhawb kev sib txuas ntawm cov ntsiab lus tseem ceeb ntawm lub cev matrix (ECM), suav nrog hom I thiab III collagn, elastin, thiab cov qauv glycoproteins. Immunofluorescence staining qhia tau hais tias qhov kev qhia ntawm Col I thiab Col III hauv HDF (tib neeg dermal fibroblasts) tau txhim kho zoo tom qab kev kho mob nyuaj, thiab kev qhia ntawm elastin kuj tseem txhim kho.
Kev sim 2: Parallel Anti Wrinkle thiab Superficial Xim Txhim Kho
Ob pawg ntawm 23 tus neeg tuaj yeem pab dawb hnub nyoog 39 txog 74 tau siv cov tshuaj nplaum uas muaj 3% ntawm cov khoom siv ob zaug hauv ib hnub los smear lawv lub ntsej muag rau 2 lub hlis. Kev ntsuas kev ntsuas thiab kev yees duab thev naus laus zis qhia tau tias nws muaj txiaj ntsig zoo los tiv thaiv wrinkle, thaum txhim kho cov xim ntawm sab nrauv thiab elasticity.
Kev sim 3: Sib piv nrog Dimension A
5ppm Pal-AHK thiab 0.05% vitamin A muaj kev sib piv hauv kev txhawb nqa collagn thiab glycosaminoglycan synthesis, tab sis tag nrho zam kev stimulation thiab cov kev mob tshwm sim ntawm vitamin A. Lub wrinkle tshem tawm cov nyhuv thiab kev ua si yog deb tshaj li cov pa vitamin A, thiab tsis muaj kev phiv.
Kev sim 4: Tsiaj qauv - UV Kho thiab Kho kom zoo nkauj
Palmitoyl tripeptide-1 hauv kev tu tawv nqaijtuaj yeem kho collagn puas los ntawm ultraviolet (UV) hluav taws xob thiab muaj peev xwm tiv taus UV irradiation. Kev puas tsuaj UV yog thawj qhov ua rau sab nraud ntawm pigmentation, thiab nws lub peev xwm kho tau ncaj qha cuam tshuam rau cov nyhuv whitening.
Cov ntaub ntawv
[1] Peptide Blend (Pal-AHK, Palmitoyl Tetrapeptide-7)
[2] Palmitoyl Tripeptide - 1.
( https://us.olivetreepeople.com/pages/Pal-AHK )
[3] Palmitoyl Tripeptide-1
( https://www.ulprospector.com/en/na/PersonalCare/Detail/135344/10245723/Pal-AHK )
[4] Sohu lub vev xaib Pal-AHK- Siv tau zoo thim rov qab kev laus thiab txo ntsej muag Wrinkles [EB/OL]. Lub Yim Hli 3, 2023 https://www.sohu.com/a/708558238_120421527
[5] Peptide Biology Pal-AHK: Kev tshuaj xyuas ntawm cov khoom siv tshuaj pleev ib ce thiab cov ntawv thov kev cia siab [EB/OL]. Plaub Hlis 10, 2025 http://www.scipeptide.com/article/2661.html
[6] Baidu Baike Pal-AHK [EB/OL]. 2026-05-06 https://baike.baidu.com/item/ Palmitoyl tripeptide-1/17039747
[7] 39 Kev Noj Qab Haus Huv Network Cov txiaj ntsig thiab kev ua tau zoo ntawm Pal-AHK ntawm daim tawv nqaij [EB/OL]. Plaub Hlis 14, 2023 https://wapask-mip.39.net/bdar/124331758.html
FAQ
Pal-AHK ua dab tsi rau qhov tsis txaus ntseeg?
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Pal-AHK yog ib qho hluavtaws "messenger peptide" uas ua rau koj cov tawv nqaij ua kom muaj collagen ntau dua los kho qhov pom kev puas tsuaj. Nws dramatically txhim kho daim tawv nqaij firmness, txo cov kab zoo, thiab smooths tag nrho kev ntxhib los mos. Qhov zoo tshaj plaws, nws muab cov txiaj ntsig los tiv thaiv - kev laus zoo ib yam li retinol tab sis tsis muaj qhov ua rau khaus.
Cov txiaj ntsig tseem ceeb ntawm daim tawv nqaij muaj xws li:
Boosts Collagen Production: Los ntawm mimicking tej yam ntuj tso collagen fragments, nws qhia rau ntawm daim tawv nqaij hais tias nws yuav tsum ramp up collagen synthesis, uas ua rau firmer, ntau plump daim tawv nqaij.
Minimizes Wrinkles: Kev siv tsis tu ncua yuav pab ua kom cov kab sib sib zog nqus thiab zoo, ua kom lub ntsej muag zoo nkauj dhau sijhawm.
Txhim kho Elasticity: Txhim kho daim tawv nqaij hauv qab kev txhawb nqa matrix, tiv thaiv sagging thiab rov ua kom cov hluas bounce.
Yooj yim & Tsis yog-Irritating: Nws muaj peev xwm zam tau heev txawm tias cov tawv nqaij rhiab heev, ua rau nws muaj lwm txoj hauv kev los yog ntxiv cov khoom xyaw rau hnyav retinoids.
Enhanced Absorption: Vim tias nws txuas nrog fatty acid (palmitic acid), nws yooj yim nkag mus rau ntawm daim tawv nqaij lipid barrier kom ua tau zoo tshaj plaws.
Cim npe nrov: palmitoyl tripeptide-1 hauv kev tu tawv nqaij, Tuam Tshoj palmitoyl tripeptide-1 hauv kev tu tawv nqaij manufacturers, lwm tus neeg
